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On Wall Street, the first quarter of 2022 was characterized by extreme volatility, as the Federal Reserve started to hike interest rates to fight surging inflation and Russia invaded Ukraine.

With the FDA poised to OK another booster for people 50 and older, questions remain: Is the evidence strong enough to warrant a fourth shot, does the timing make sense, and will there be much demand?

The Food and Drug Administration has authorize fourth shots for those age 50 and older. The move is aimed at shoring up waning immunity, especially as the U.S. faces the possibility of another surge.

Russia says it put its nuclear forces on a higher state of alert, and Western officials have raised the prospect of chemical weapons attacks. How serious are these threats?

Ukraine's president has been sharing videos of destroyed hospitals — calling on the West to impose a no-fly zone. U.S. Secretary of State Blinken says the goal is to end the war not to expand it.

Russia's war on Ukraine and the resulting oil price spike have forced the Biden White House to consider all kinds of measures for fossil fuel that it once would have shunned.

College basketball's March Madness has begun, the latest on American basketball star Brittney Griner who's detained in Russia, and a controversial trade shakes up the NFL.

NPR's Ari Shapiro talks with John Eligon of The New York Times about the catastrophic flooding in Durban, South Africa.

In an appearance with GOP congressional leaders at Camp David, President Trump addressed topics ranging from his own mental health to his legislative accomplishments.

As multiple movie sequels come out this year, Vulture recently ranked the 101 best movie sequels ever made. NPR's A Martinez talks to TV and film critic Matt Zoller Seitz who contributed to the list