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Airstrikes have helped push back the Islamic State in some places, but the group has gained in other areas. Pentagon officials say the U.S. operation may need another two years or more to succeed.

A CDC advisory panel concluded the nasal spray vaccine is so ineffective that it shouldn't be used by anyone during the 2016-2017 flu season. Until 2015, the spray was the top choice for kids.

Donald Trump named a conservative media provocateur to lead his campaign — in the third major shakeup during the election season. David Greene talks to senior Trump adviser Boris Epshteyn.

Former Vice President Biden announced Thursday that he will run for president. The 76-year-old former Delaware senator immediately becomes a top contender vying for the Democratic nomination,

The former vice president, who saw Barack Obama win twice on a unifying message, is betting that will win out over anger. Will that be enough for Democrats, who feel they have good reason to be angry?

Thirty-two years after a deadly earthquake, a magnitude 7.1 temblor rattled Mexico City and surrounding areas. Residents had marked the anniversary of the 1985 quake earlier in the day with drills.

The bidding period has closed for the companies hoping to design and deliver the president's signature campaign promise. Here's a glimpse of some proposals — from wire mesh to 30-foot pipe organs.

The Supreme Court hears arguments on the ban Wednesday, and a bipartisan group of former national security officials from the Reagan to Obama administrations are urging the court to strike it down.

Females make up less than 30 percent of the the country's labor force. But one nonprofit is providing restaurant and cooking training to vulnerable women who have been shut out by Moroccan society.

Amazon is working on a whittled-down list of cities where it might build the second headquarters. Among the bidders, Washington, D.C., stands out for competing against two of its next-door neighbors.