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Never known as a big-venue speaker, Hillary Clinton will face a make-or-break moment Thursday night with multiple pitfalls, varying objectives and a variety of critical audiences.

John Hinckley's not-guilty verdict prompted tighter restrictions on the insanity defense. Civil rights advocates say that means seriously ill people are imprisoned without adequate treatment.

Practicing surgery on a piece of pork — that's how some doctors are learning to implant a new drug that curbs opioid cravings. It's not a skill set typically used in addiction medicine.

Most people know not to eat raw cookie dough. But now it's serious: 46 people have now been sickened with E. coli-tainted flour. Here's how contamination might be occurring.

At about 1.6 million years old, the bone is the oldest known example of a malignant tumor in a human ancestor, and it reinforces what scientists already knew: that cancer isn't a modern scourge.

Health officials put blood donations in South Florida on pause until it's known whether four cases of Zika virus were caused by mosquitoes in the U.S., or until blood donations can be screened.

Syrians in Aleppo don't trust a promise from the regime and its Russian allies to allow residents to safely flee through new aid corridors, But some are desperate enough to try it.

It's the fourth and final night at the Democratic National Convention, and Hillary Clinton is set to take the stage, to accept the nomination and make the case for her White House bid.

According to Border Patrol, more than 120,000 unaccompanied children arrived in the past two and a half years, many seeking asylum. Some young immigrants are now trying to use a new visa category.

"I have no idea. I can't even hazard a guess to phylum," one scientist says. The curious orb was found and captured during a recent Nautilus expedition near California's Channel Islands.